One observation noted with my first HC attempt (may he rest in peace), is that the playstyle in HC seems much different. Running away to live and fight another day is o.k. In SC I can go toe-to-toe and use brute force. If I die, I just come back and do it again. I also need to be more aware of survivability when selecting gear and abilities. Focusing on raw damage can leave you vulnerable.
Anyway, I think this will be a fun learning experience. Thanks to you regulars for putting out a lot of good advice in your posts. Us newbies appreciate it.