Firebats - crimson - Channeled Massive AoE dmg
Grasp of the Dead - Alabaster - AoE Slow, a little dmg, and health globe drops!
Soul Harvest - Alabaster - Increase weapon dmg and apply more dmg
Sacrifice - Crimson - AoE burst dmg that will increase overall weapon dmg
Zombie Dogs - Golden - Meat shield that can be sacrificed to increase dmg and give health globe drops to increase survivability, cast sustainability, and further increase weapon dmg.
Hex - Obsidian - CC and create a ticking time bomb who's dmg is increased by 20%.
Zombie Handler - 1 more zombie dog for more meat
Circle of Life - Mana!
Gruesome Feast - Dmg!
Best combo to give health globes a boost that no other class can receive!
I know alot of folks dont like hex but, i do because of its runes at versatility. Hex with obsidian will remove 2-3 demons from the fight permanently, and turn them into poison bombs. The increased in 20% damage to Hexed targets will allow me to down these units with Zombie Dog sacrifices, Grasp of the Dead, Soul Harvest, and Firebats quickly to increase AoE dmg output.
Another upside to hex are the different runes. For boss fights i can use Golden Rune for heals, or when fighting elites Alabaster to increase dmg. I think Hex is better than what people give it credit for. Its versatility makes me consider it in all of my builds.