When I play ranged classes, I prefer not to put any skills on the left mouse button because it's too easy to misclick and end up walking right next to the enemy you were targeting. Also, I find holding shift down all the time gets tiresome, and sometimes I just plain forget about it. But, that's not the main reason I'm posting.
My concern comes with using the fundamentals passive along with 6 active skills. As it is now, the 5 hotkeys and 2 mouse buttons allow space for the 6 active skills and an item (presumably a health potion, but others have also argued that we need more hotkey slots for other items, which I agree with). Anyone who uses fundamentals will have all slots taken up by the basic attack and 6 active skills, leaving no room at all for potions or other items.
Does anyone know any more info on this? I haven't found any updates in the past month or two regarding whether Blizzard plans to tweak this. Do they expect us to constantly swap skills on a hotkey, or to constantly open our inventories to use potions and other items? It doesn't seem that Blizzard would expect us to simply drop fundamentals when we unlock all 6 skill slots, since I thought they wanted to make every skill useful throughout the game.