Why use silly life regen when you can just spam Diamond Skin with no cooldown, along with massive amounts of damage from Explosive Blast spam and elite pack stunlocks?
high crit rate
fast 1h weapon
int, ias, crit damage
mf to taste
life regen unnecessary
Poop out Living Lightnings. This hits enemies a zillion times a second and applies Venom, which hits even more. This results in well over a hundred hits a second, all of which can crit. These crits trigger Critical Mass, resetting your Frost Nova, Diamond Skin and Explosive Blast cooldowns practically instantly. Also, Prodigy gives you vast amounts of AP to fuel Explosive Blast spam. Arcane Dynamo triggers constantly and powers up almost every blast. Frost Nova allows you to literally stunlock elite packs, even with their massively reduced duration. Also you are invulnerable because Force Armor reduces damage so that Diamond Skin lasts through 12-13 attacks, and Diamond Skin can literally be spammed.
Variations: Swap Frost Nova for Wave of Force, different Explosive Blast runes, swapping up Prodigy for whatever. This one is optimal for general play though.
Act 3 Inferno is easiest to farm but it can also handle act 4. Problematic elite mods are Molten and Fire Chains, but they can be killed by stunlocking or careful play. Invulnerable Minions should generally be skipped unless the other mods are harmless.
tl;dr: Constant massive AOE damage, nova stunlocks, infinite health against anything but fast DoTs.
Also, Force Armor still works, don't listen to the lies.