The above video demonstrates the problems thousands of users have been experiencing whilst trying to play Diablo III. This problem exists over many different combinations of CPU/GPU and does not appear to be related to hardware as I have observed on many different forums from users including this one. I have noticed that there have been many threads related to this issue closed as it stems back to the beta and would like a Blizzard employee (blue) to simply acknowledge this problem and to give feedback as to any possible solution if available on the side for the user and to let us know if this is currently being worked on.
I myself have experienced this issue and can say that it has ruined the experience of the game for me. I have spent hours installing the latest drivers and attempting all of the many fixes on the web and still the problem persists. I should note I was able to reduce the stutter by turning off in game shadows but the problem is still present.
I installed the game on another laptop (i5 sandybridge HD3000) and although I had to lower a lot of the graphical settings the gameplay was buttery smooth on the same network so its not a latency issue (45ms). This is very frustrating as I have a computer more than able to handle this game and have experienced no such issues in any other game including Blizzards own SC2 and WOW.
Samsung Series 7 Gamer Laptop
i7 2670QM @ 2.2 Ghz
Win 7 Home Premium 64bit
All latest drivers installed. 100+ fps on max settings @ 1920x1080, (40ms latency)