LClick - Bola Shot + Volatile Explosives
RClick - Entangling Shot + Chain Gang
1 - Rapid Fire + Fire Support
2 - Multishot + Fire at Will
3 - Sentry + Spitfire Turret
4 - Companion + Spider Companion
-Cull the Weak
I'm building towards a homing rocket theme just because that seemed suitably ridiculous. I did not expect how much I would like Bola Shot though, the damage output is kind of crazy compared to the other generators IMO. Plus I can Bola Shot > Entangling Shot and the snare hits RIGHT before the Bola explodes for the bonus Cull the Weak damage.
And I tried Ball Lightning but the AOE is really narrow and it moves so slow, Multishot is much more satisfying in the way it just drops a room of enemies instantly.