The game gets to a black screen with all of the background music playing. It sounds like it is reaching the login screen but is unable to display anything. If I exit the game, and reset game preferences in the launcher I am able to get the game to load without any issues. I have to do this every time I want to play the game if I leave it with Optimus settings.
If I switch the video settings over to Discrete Graphics in the BIOS, so that it is only using the NVidia Quadro 1000M graphics processor I can load the game without any issues every time. I have not experienced the issue with the machine since I switched it to dedicated graphics.
It seems like the game has a problem when the system tries to switch from the onboard Intel graphics processor to the NVidia Quadro processor after the initial login.
Figured there might be a few people here that could use the information, and possibly get a fix from Blizzard in the same vein.