This bug has been fairly consistent for me since the game came out 2 weeks ago. Periodically (at least 5 times per playing hour), the game will essentially ALT TAB to display my desktop mid-action. It only briefly shows my desktop (2-5 seconds) and then it resumes normal play. I cannot interact with my desktop when this happens as it is just a brief flash. This is kind of an annoying bug because I have died several times as a result of the game continuing but I cannot interact in anyway while the ALT Tab process occurs.

My gut tells me it is something in the video processing but I am not sure. This issue has happened on all 5 classes of characters I have. It has happened on many different quests and/or Acts (I am in Act III on normal).

I have the full export of dxdiag if you need it but here some basic information including video driver info. My GTS 250 drivers and DirectX 11 is up to date.

System Information
Time of this report: 5/29/2012, 19:42:15
Machine name: --------------
Operating System: Windows 7 Home Premium 64-bit (6.1, Build 7601) Service Pack 1 (7601.win7sp1_gdr.120330-1504)
Language: English (Regional Setting: English)
System Manufacturer: Dell Inc.
System Model: Studio XPS 7100
BIOS: Default System BIOS
Processor: AMD Phenom(tm) II X6 1045T Processor (6 CPUs), ~2.7GHz
Memory: 8192MB RAM
Available OS Memory: 8192MB RAM
Page File: 3522MB used, 12858MB available
Windows Dir: C:\Windows
DirectX Version: DirectX 11
DX Setup Parameters: Not found
User DPI Setting: Using System DPI
System DPI Setting: 96 DPI (100 percent)
DWM DPI Scaling: Disabled
DxDiag Version: 6.01.7601.17514 32bit Unicode

DxDiag Notes
Display Tab 1: No problems found.
Sound Tab 1: No problems found.
Sound Tab 2: No problems found.
Input Tab: No problems found.

DirectX Debug Levels
Direct3D: 0/4 (retail)
DirectDraw: 0/4 (retail)
DirectInput: 0/5 (retail)
DirectMusic: 0/5 (retail)
DirectPlay: 0/9 (retail)
DirectSound: 0/5 (retail)
DirectShow: 0/6 (retail)

Display Devices
Card name: NVIDIA GeForce GTS 250
Manufacturer: NVIDIA
Chip type: GeForce GTS 250
DAC type: Integrated RAMDAC
Display Memory: 4069 MB
Dedicated Memory: 997 MB
Shared Memory: 3071 MB
Current Mode: 1920 x 1080 (32 bit) (59Hz)
Monitor Name: Dell ST2410(Digital)
Monitor Model: DELL ST2410
Monitor Id: DELA05C
Native Mode: 1920 x 1080(p) (60.000Hz)
Output Type: DVI
Driver Name: nvd3dumx.dll,nvwgf2umx.dll,nvwgf2umx.dll,nvd3dum,nvwgf2um,nvwgf2um
Driver File Version: 8.17.0012.9573 (English)
Driver Version:
DDI Version: 10
Driver Model: WDDM 1.1
Driver Attributes: Final Retail
Driver Date/Size: 2/9/2012 22:43:00, 17642816 bytes
WHQL Logo'd: Yes
WHQL Date Stamp:
Device Identifier: {D7B71E3E-4555-11CF-BB5F-9F251CC2C535}
Vendor ID: 0x10DE
Device ID: 0x0615
SubSys ID: 0x0593196E
Revision ID: 0x00A2