Well just tested the ptr for few more hours, and this thread is already expanded for feedbak ill put my feedback on ptr here.
As far as it go for the "defensive nerfs" meaning seize the iniatiative, i had no problems with it, i was already expecting it, and ive been runing act on 1.04 without seize for testing, sure my monk can be considered in "high end" gear, less geared monks may feel the changes more heavly.
Monster powers above 5 are really chalenging, makes you play on your toes insted of right clicking everything to death, it seems that fire chains affix is dealing more damage on those levels what is a good thing becouse since 1,04 that affix could simply be ignored.
The patch is adding much more depth to the game in therm of were to farm and how to build your charcter towards that, im not gonna discuss class changes that i wish to happen becouse the other posters already said enough imo.
The only thing that is bad, maybe strangely desined, is the reflect damage affix, of course im aware that its no loguer dodgable so i would fell it more heavly, thats not exactly the case, some reflecting monsters , dont reflect enought to overcome my lifesteal (2,4%) some barelly do and my life starts to drain slowly, and some completly and utterlly obliterate me with no chance at all, to the point i cant touch then without loosing 1/3 of my hitpoints, its really weird. This can happen in any mp i tested then all across the board, meaning the reflect power is not correlated to mp levels. More on that i was standing at 637 all resist, and 4400 armor (w/ new enchantress buff), 151k base dps.
Other than that, i feel that the hp scalling might be a litle overtuned but nothing system braking.