Resolve, a Monk passive: "Damage you deal reduces enemy damage by 20% for 2.5 seconds."
Bad Medicine, a WD passive: "Whenever you deal Poison damage to an enemy, their damage is reduced by 20% for 3 seconds."
These two combine for a whopping 36% total damage reduction from every enemy that you come into contact with.
Mantra of Conviction w/Overawe, a Monk skill: "Increases the strength of Mantra of Conviction so that enemies take 24% additional damage and 48% for the first 3 seconds."
Hex w/Jinx, a WD skill: "Hexed targets take 20% additional damage."
Mass Confusion w/Paranoia, a WD skill: "All enemies in the area of Mass Confusion take 20% additional damage for 12 seconds."
These three skills applied together, increase total damage taken by affected enemies by ~71%. Coordinate this combo against Elite packs, throw in a Seven-Sided-Strike, and they disappear!
This is my main build in-case my Profile doesn't reflect it (I play around with skills a lot)
Any thoughts or other interesting 2+ character combos that you wanna share? :)