We all know that some of these heroes are now tearing their scalp apart, gouging their eyes out while screaming horrendously from the madness of battling the Prime Evils. This is their consequence for facing such forces for too long.
Now we have the Nephalem, who are potentially more powerful compared to the angels of the High Heavens and the demons of the Burning Hells.
What could happen to them as they battle the forces of hell? Would they succumb to madness much like the heroes of the past or: