I noticed some time ago my D3 client would randomly restart the background music and/or change to another song constantly. Sound effects stop mid-way and restart. It does this both in game and at the menus. At first I thought it might have been some error with my SteelSeries mouse driver, but even with it uninstalled and the mouse disconnected it still can't play more than a couple seconds of music before changing.
I haven't played much D3 of late, but the problem still persists after the recent patch. It makes the music unlistenable (simple and obvious solution is to disable the music, but that hardly solves the problem).
Changing audio settings, lowering graphic settings, using internal audio instead of my USB DAC, nothing works. I've done a full delete and reinstall of all Diablo/Blizzard Shared files to no avail. The only other issue I am experiencing with Blizzard stuff is the gradual slowdown to 0 FPS bug in StarCraft II.
Mac OS 10.8.2
i7 @ 4.4 GHz
16 GB RAM
SSD for storage
GTX 650 2 GB
FiiO E17 USB DAC
I'm pretty sure it isn't anything on my machine as I've seen reports of this problem on Windows machines on the EU forums.