Diablo® III

Do offhand and main hand matter?

Does it matter if you place item A as main hand and item B as off hand or vice versa? I know it makes a difference for barbarian (because of some passive), but I don't know if that is the case for monk.
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depends which skills you're using...

if you use wave of light and/or cyclone strike you'll generally (there seems to be some exceptions) want your higher average damage weapon in your mainhand
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