Diablo® III

Push to talk with skype while in game?

On OSX skype has a keyboard shortcut to mute the microphone. It works great while outside of game. I believe it's command+shift+m. However while in game, that keyboard shortcut doesn't work. Is there a workaround to this?

I've tried other program and it's certainly possible to have keyboard shortcut work while in game. For example the shortcut for Ventrilo works while in game.
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