I was playing an arena run, and placed a Twilight Drake beside a Dire Wolf Alpha. After that, nothing I did responded. For the longest time it was perpetually my opponents turn from my perspective, but kept doing my emotes as if it were my turn, waiting on me. Eventually it was as if the game finally caught up and I watched all of the opponents actions happen up to and including my defeat.

Screenshot if it helps:
http://imgur.com/2x7RLig