I started out with the beta launcher, but the game's worked since then. I'm on a mac, too, if that matters.
Update: I tried uninstalling and reinstalling, no effect.
Update 2: Upgraded to Mavericks from OSX 10.8.5, now it works. Oy.
"We couldn't launch %game% because your operating system wouldn't let us write to the registry.
Error: BLZBNTBGS8000000A, BLZBNTBGS80000022"
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