Also, inspiration does matter. If I were to make a parody mocking emo kids and someone mistook it for mocking people with depression, it doesn't mean I'm actually making fun of people with depression.
But if Depressed people feel that you are making fun them, your response should be to seriously look at what you've created and understand that it is certainly possible to cast too wide a net and hurt people who don't deserve it.
Just because you didn't "mean to" hurt someone or say racist things doesn't mean you aren't being racist. There's a reason there was such a huge backlash against Brad Paisley's "Accidental Racist" song: "I didn't mean to be racist" is not an excuse.
Because racism is so intrinsically baked into the fabric of our society, it is possible to do racist things simply by using certain images and symbols, and even if you claim (maybe even sincerely) that you didn't mean those symbols to be racist, the symbols themselves are racist. The Confederate Flag is racist because it was established as a prime symbol of a nation whose primary raison d'etre was to keep non-white races inferior via slavery and discrimination. Even if someone claims they are just using it to show their "southern pride," the symbolism behind it is still there, and still hurtful.
Likewise, The Pygmies wear grass skirts, use flint weapons, are named after a diminutive used specifically for certain African ethnic groups, and are placed in a jungle environment. They employ racist sterotypes about African people. Adding some extra "roadie" imagery and claiming that's what they actually are doesn't erase that.