Since starting these runs I have beefed up to 65k dps and 65k hp. Farmed close to 100M total from this run and I will continute to do so untill I find that one hand dagger with 1200dps open socket and 90%crit :P
With the boost in DPS I'm completing these runs in about 20-25 minutes depending on the type of packs. Basically more snakes equals a longer run.
Just to preface here are my stats
Resist All: ~400
Mana Regen: 0
I don't know if this has been documented here or if people have been doing this without my knowledge, so sorry if this is old news to anyone. I have recently started refining a method for MFing act 2 in the most efficient way possible and I think I have found it.
Here is what I call a "VotA Run" (Vault of the Assassin Run)
1.) Start on the "Black Soulstone Quest"
2.) First WP: Road to Alcarnus, head here, over the bridge and there is one guarenteed pack, but typically two. Kill these two and go back to WP or town.
3.) Second WP: Black Canyon Mines, head here and look up first, if there is no pack up from the WP, head down and accross the small bridge. From my experience, there are ALWAYS two packs very close to this WP and are usually easy to kill, fallen and bees.
4.) At this point you have either 3 or 4 stacks, If you have three, spawn at the Khasim Outpost WP and run down, there is usually another mob here.
5.) Once you have 4 stacks, head to the sewers, there is ALWAYS either a pack of flies or snakes down here, ususally very close to the WP.
6.) Now, heres the not so fun part. If this is your first VotA run, you are gonna need to find the Vault, and it can take a bit of time. This will make your first run a little longer then the rest. Spawn at the Desolate Sands WP and start exploring. I find that the vault is usually bottom left from the WP or top right, to the right of the bridge that leads to the next area.
7.) Once you are in the vault, have fun clearing the most densly packed Champions in the game (that I have found anyways). On several occasion I had to take on two packs at once because they pretty much spawned on one another. There is NEVER less than seven packs in this area and I have seen upwards of 12. The trash in here is also very easy mode and there isnt much of it.
Now heres the trick, when you are done with that particular run, leave the game but DO NOT change your quest, now each time you rejoin your game you will be in the vault :D. From here, TP out and go from step 2 making sure NOT to use town portals, just the WPs. When you have 5 stacks, use the WP in sewers to get back to town and then use your original TP to get to the vault instantly.
I started doing these runs over the weekend and I have made over 20M in drops since saturday. I'm typically finding at least one rare i63 per game and multiple i62/i61. Last night I found nats boots, a rare heaven hand and a rare demolisher in the same run, lucky I know but still, this is a VERY potent run.
Well there you go guys, go have some fun and good luck finding that 100M rare :D